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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1b51337f9cf8c247fc408267eef640910bb778d7d4181f6bd00db2af4043e617' 
  AND token = 'DsdHaX69HMmqo1aOVxcXCVsDFQwwsvfTyTZED8g0Ir0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00048

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}