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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'affbfb0b4719d569437962d2cb424d34463bb52cc4b510985bd4ded55bfbb1fc' 
  AND token = 'TbDIjBdaIFr1Pw4tTz7BZjvSRL1Uqs0a+bmZD+JZjjE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}