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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9889e7d09d6e95f2e93c2b0cc8d7888e6afb709560325e5e6797e8e05d03bd16' 
  AND token = 'o2uPHRQybSApbQbAvW7GV+m0HZx1ODAR+M2L447s9dY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}