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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '384d2b7e137e69dd70593721dda900cba859b97cc0cb0e6e47561930e252656d' 
  AND token = '/U4UmPsDrD4COnayBsiQYRtF9MtqXBxTOxXFtaVC4sQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}