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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6219a2b6bd11a91b1b211b0a3fedc222588a6fd61ca4ba50a3a0f02bdcc22424' 
  AND token = 'ofVL8/orTBXlueF0wuOToBevN8vM18Txy78Pmb/tyAA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}