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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '390ebc54a3d020008a243be7400bc3a8eb0b3a5a3bb22e4a141f0cc76671f963' 
  AND token = 'oWwnTUaO0lGNJS9u/MBISKnpaoF0QelfPMGHHAF4t7o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}