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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b49c3c59e0b7a8af9048d91717f4f15ebb35d86a226a4e3e4175f3d00ab37b25' 
  AND token = 'K6vnp5y1aL8bVv5uLX2xr1pnPjvEX+oXcpMTlTwl0jo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}