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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cfc64f09134c803f32b8ec6091022f7c54d17cf5be16eda7cdc36cb234bc73bb' 
  AND token = 'OQCq3NtTh35Io+MiLpD3Fiv2WGtCMTlR1RMZfjrLBYg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}