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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '34b7c862b20652977dbc2bf29dac4064e5c09ec0b51343d4f60025898b64155c' 
  AND token = 'U1Vol4hI17meAk+kSK3/6CUtNIXFQ+Jl9PqOBoE7ESI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}