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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'af59c6940dc9d11722e96f0ead515f434ed995ce8df95e58b23adabb8a8e5049' 
  AND token = 'C/ICpZbiiPtkz/r6trwIcO0fKdPq+kXEFvXOgzMKpwg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}