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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cf18b8b990e1350d404d9d4c396b30c5afa9ea1a5cf75f37818480f133387eb8' 
  AND token = 'WIcv+rH65M7F2deuCPREsNjqJIRjNLPdltIdUnN9asQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}