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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '434add640b898e8f1b001a32aa96c8d8002fab7496f066d26365f776cb32c6eb' 
  AND token = 'hDuSUDTxIwE8UnegHl8mJpdlYVPi8GRDyWodhW6n6XA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}