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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5106d2ca17247c31c38d4c3caca9fff2f24e8e8ec1b2561462da2de3ddaa837b' 
  AND token = 'ZIGSHu6fnusQloYOxC06wEX3hB5SPtb0GxUWmpBUOes=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}