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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '55d5a8b7e1a0816ba23e8bfa05096a1bf91229cccc7847f3a03ff1af733edddf' 
  AND token = 'Zo90AS5GCExHDVRH+VBHe7f+PuX7XP4cLHnPBkD9mm8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}