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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '46fe0822a750f2e1ec01e9b0d6d870cce24ba2cef9cccefe9e81a7f6c86aa0bb' 
  AND token = 'sJUZyk9Yi5FVIKxO3IAZQBI/t0QtTwnIHfKdiqtkUF8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}