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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a54be390b08daf2ba33a209fb6b6d480f04ee45b41db07cff449496ca196d3e7' 
  AND token = 'u3tvoddTmf8dUMerYRVh0pS8uO2jSIPvmPbnDVimV+Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}