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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e58382a767cf18b773ca6b6d046da9492498849f66dd8044406ae93e87cd709e' 
  AND token = 'pn1TdJ6IabboiLEEnH+Lz89YAXLBnSA3GtgblF2y6Zk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}