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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '330ef20ee73459c10999123333e49b648e9fbec09aa5a121175fd04c89166ac8' 
  AND token = 'EpxPKusGON8G8J2vpV0fOS9cqmr8Ztm4zuO300Y6z4g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}