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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '150df7491f5ba5b44a44896f07ace58cd8b5379dd3ef1ab9a01f467d0ecd833a' 
  AND token = 'cHIrMOy21lXFG9bqkZYENwD/XDCk9HvWuJ9v7RJbJ6I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}