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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5e201921d6b2e1fae991f112eb8c20163732fb39592ffc97367ddccb46dd7482' 
  AND token = 'yOvE2FBX9XTMimOex7tCU4mSSVyK+o1o6RR2DZ3ILqY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}