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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '22236a0e14225b17c7db7d4a35621971a49c041f8dd6ad29e82e8caedfcd09ee' 
  AND token = 'Cn6vfCo3nFnozWJjBoqDD8u3FR6Ah990kZtST0ci4tE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}