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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8ef90e7ea764e83d22770d71737028b861b1bbbcf072ba305c162110c2382f40' 
  AND token = 'KVt9S6+plFygyPL5KjBfr2qF7prjPddSZ8jzWGLyfSE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00052

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}