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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '56954622301cbe59bfb5e83ae33b4130a6821a609b2be2efaf6b780682518fba' 
  AND token = 'TLkpm5H1lErz0n0tZEQMQEQSk0XNZBhQkdmuyew4DSs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}