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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '11a38efc9cbba83c738a911273f80058213fb5f944a1f0acec2d1c87c1ce6421' 
  AND token = '4N48qGFRBCVCBUszWEhRS2pEuL2OrL78GzU9A2VgPdg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}