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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '50b7f5701dbe31198f0b486882e0fddba93311bee8244f6022f7821fb00ff8df' 
  AND token = 'hYQ1DASUhxVs1/Cl3jMkAZ/QRlZFqCg3EtPtnqH2kDA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}