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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0a820dcc49eb39e116e07873cf5bdc07bccd90f604e5adf8d7a779f2905912f4' 
  AND token = 'yHy2YPLV56wdv/L+r/gxexfmlXi2Jju9H1QhWD3DeEI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}