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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f04a65e7c0efcd355e3972484ae42f6a611c0b802323699098228adfa28e6464' 
  AND token = '7OWImHkfTKyMhym4h7LzOUOsIwgrkxNk4MkxTTXWdtI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}