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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '434ec64d16f4a2cd381363028a9220552239f533a1070d9fa8b9a66456342b7d' 
  AND token = 'o2fdVA45J0Cjva02h9Mo2PfUUQjvM0YGmi0XAQ37WUg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}