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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e66beceb3daefd4e6f2c174503bdc534f77bcdced04279892f11da2396d40f10' 
  AND token = 'wPMhl8GD9yImIOoElVlacE8kFKar+uZ+sNooR6KzbFw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}