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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd116f6aa2e090b446b5bbb6cce433caccd7eeb9a9827496aabb4c91ee6ef8450' 
  AND token = '4naQwf/o26txgO4hkQ+2jmTqw+eVnPSKtWOunpYfpP8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}