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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e3eeab0b8a5d1fa4fb0fedf9e2e4ef625e83cca30dfb55b196ac587f36a9cb03' 
  AND token = '/MmdC1k6qqjaU5GDj3uQlHvTqoXCWPRC2OlL6Jaz3Lk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}