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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fed95b0871d3e48693ab6bca33f826e02c47d9bee0ad87029fdd3ed53c0620dc' 
  AND token = '+qDV0w8BM0PTZ/XFrhsFuf7ZvsH1st4fde58YZjUWwk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}