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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9245498a3ab7f8e3580d7e1f0c0c54e6183fb7af20ab4b12c11205e39e7701f2' 
  AND token = 'Q/i81a8OHfYo/u2ILvsVmYhDGRMtWXcLO78Fy+DfuX0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}