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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7edddf737ab3f48ac8912467110b367aeb7cbc52f1768c0f19d9bb152e1293de' 
  AND token = 't+ZSGH1tO6lpVbQBHxhR+hxSjUEoJ505SreXMTwPtWA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00051

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}