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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4a0423cc19a0ad80ad3c2a3459665a4a6d2fb39901e2631d361bf7ad1a116465' 
  AND token = 'NSgbnUvjfs2AhFL6koRM29fRuSPDB48D6PT6PdWR2KI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}