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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3efd0670d48ea323a463fee5b16a86002f3a7b1f3e7f8b29c2cf3017866b9586' 
  AND token = 'LX4qaURChwJIb4U5LTId8rUJnYqoB77B5neOI8rZxYg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}