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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0538cdddba5b90a002146deda796280b20a18279e32c5ed9a9b0489264687d3c' 
  AND token = '8BOiDA5JPXLUfmuCOwS0XlQX+a2JdCX2CCIjl8v9IlE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}