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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a591b2e3fc5bc2b8f4774e77b4943386e935a264241ae5c8202a6e27bc4e2c6c' 
  AND token = '12/LKRzG5TYgibnHqveiCIs6ZBvtvRTRpd09UhT72gw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}