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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c6d2b03196b7a0b5dd85e16a70c6ff0c5fe824d3ecd1cc2e2c39d78ef2b47ddc' 
  AND token = 'S524FJt/2crx1+S+2oHDddQ0zAsT8Jpa+7v9sXPqo+A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00052

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}