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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '540f62495b564c643648851e836f740f4621b13c3647a73d8ed3751aeb1b280b' 
  AND token = 'lXS7R8LjCho/3kIO3pU98zZBWrnqtcp8GMDPRe555ks=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}