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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '71c333c944e7c318a2c9ffd6e96f5e02e7c58b37f2e3e46e75a5160584b67377' 
  AND token = 'tKsCt27kmQUhfxNXinPKtRWxVwps6+lduWgFEIhJCQE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}