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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7af1b322201441adf958e0609332f3bcf5df31a99195cc11552fa2ba7ad0296c' 
  AND token = 'STdXPAIgwqPSkzfo8y7US6bF7he+GwB54i1OTuqsBhI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}