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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2a9b824453d2430bbb4c3fd9fd94af647970dcb195de0bd74f59b4895d7cb7f4' 
  AND token = 'Xwn2+qlbikf56TEchyDYo1/DSjj0eCx/hGs8Z/wTUFs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}