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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e8541340fce7480ccd249688974299df1322eeba20496eaa18fa1c3f77521d49' 
  AND token = '/PCpjs/HkhHw5Fr5TxlzWSDNpAGQXsYvQXIs/bfys8c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}