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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '80ec9930266d1fe986a3387b73c2e7e8fed55472e35e0edce01b915de0a2eb54' 
  AND token = 'J45bLDGjTHyekJ0Muajgdx5RjYzl+dCeB0fUe0m/9ZU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}