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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5e35b4838af66dbcd4fb6aba64e3ca89981832e1838a575af7ab9844b9719b6f' 
  AND token = 'osy8gQK+YYX1z2BjP7yDV1c20REOMAVBn46reXPxGsU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}