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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '42a527c9254b7f952d456a95ad7a71a83f5c137909c761733fa70fa807859369' 
  AND token = 'dVr56axzfoI+9uQUsgUrhIG2q39dkzGZA8iMgqq4ZYc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00066

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}