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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9a86ecd8144e99502ec3650ce402f7d45aeef2e0ca01a4c60e758d37d54e3760' 
  AND token = 'ZEHjwJct5y6M1jl2WIRJJQZoWJDe0evwvMFi6x5EJp4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}