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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'afd3b2f01dba54eeee4efd7c7eb533c9315d36e6a1ad3a520f6e02074810a049' 
  AND token = 'PkSxM2xzSS5yZJQV6WZTLU7JGnpJCczzrOLGdagcfsE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}