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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b1f14dae3dab190f0305c321a8f0c919f1df17a6876349be8daab65f1e5409ce' 
  AND token = 'GrlXJpVM1Ri1/dQCnFa4hawvMUcMq/7DmhtiziMWxGM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}